If you have set-up to send email using SMTP and get an error connecting to the SMTP server (maybe with the error 10061 reported when sending a test email) you should make sure that your firewall has been configured correctly.
You should allow the product (e.g. Order Processing for Actinic and/or Automation for Actinic) access to port 25 to your smtp server across your firewall. You should use the same settings as are defined for your mail client (e.g. Outlook).
If you use BT as your ISP they, by default, block all reply addresses (e.g. firstname.lastname@example.org) from any domain apart from theirs. For example, by default, they block mole-end.biz, so no email can be sent with a reply address of email@example.com.
To resolve this problem you need to contact BT (0845 600 7020), selecting options 2 and then 2 and asking for your domain to be added to the 'email relay'. You need proof that you are allowed to send email from that domain (e.g. the address in Nominet matches your billing address). Once added you can send email again (which can take from 5 minutes to 24 hours).
This problem also affects Outlook, Outlook Express and any other program that sends email with a reply address other than your bt account.
Another approach, if you are using BT as your ISP and having relay problems, is to use the email server from your Actinic site (if you have one).
If you get the error
Can't send message (553 sorry, that domain isn't in my list of allowed rcpthosts (#5.7.1))
it maybe because the login authentication type to Automatic and the wrong smtp login type is being found. Start by changing the login type to LOGIN. If this fails set this to CRAM MD5, PLAIN orÂ NTLM.